BEHAVIORAL SCIENCE TRACK AWARDS FOR RAPID TRANSITION-NIDA

NIH GUIDE, Volume 26, Number 9, March 21, 1997

PA NUMBER: PAR-97-046

P.T. 34

Keywords:

Behavioral/Social Studies/Service

Psychology

Social Psychology

Drugs/Drug Abuse

Cognitive Development/Process

National Institute on Drug Abuse

PURPOSE

The National Institute on Drug Abuse (NIDA) invites newly independent

investigators to submit applications for small-scale, exploratory

(i.e., pilot) research projects related to NIDA's behavioral sciences

mission. The Behavioral Science Track Award for Rapid Transition

(B/START-NIDA) will provide rapid review and funding decisions of

applications. Experimentally-based research applications are

encouraged across a wide variety of behavioral factors in drug abuse,

including neurocognitive, cognitive and perceptual processes,

psychosocial, and more broadly motivational, social and community

factors in drug abuse. Given the role that drug abuse plays in

HIV/AIDS transmission, studies applying basic behavioral science

models and methods to address this issue are especially encouraged.

HEALTHY PEOPLE 2000

The Public Health Service (PHS) is committed to achieving the health

promotion and disease prevention objectives of "Healthy People 2000,"

a PHS-led national activity for setting priority areas. This PA,

Behavioral Science Track Awards for Rapid Transition-NIDA, is related

to the priority area of alcohol and other drugs. Potential

applicants may obtain a copy of "Healthy People 2000" (Full Report:

Stock No. 017-001-00474-0) or "Healthy People 2000" (Summary Report:

Stock No. 017-001-00473-1) through the Superintendent of Documents,

Government Printing Office, Washington, DC 20402-9325 (telephone

202-512-1800).

ELIGIBILITY REQUIREMENTS

Applications may be submitted by domestic, for-profit and non-profit

organizations, public and private, such as universities, colleges,

hospitals, laboratories, units of State and local governments, and

eligible agencies of the Federal government. Racial/ethnic minority

individuals, women, and persons with disabilities are encouraged to

apply as principal investigators.

To be eligible for a B/START-NIDA award, the proposed principal

investigator must be independent of a mentor at the time of award but

be at the beginning stages of her/his research career. If the

applicant is in the final stages of training, he/she may apply, but

no B/START award will be made to individuals in training status. The

proposed principal investigator may not have been designated

previously as principal investigator on any Public Health Service

(PHS)-supported research project. Previous receipt of National

Research Service Award funds (i.e., Institutional Training Grant or

Individual Fellowship) is permissible. Foreign organizations are not

eligible to apply.

MECHANISM OF SUPPORT

The funding mechanism that will be used to support this initiative is

the small grant (R03). Each award is not to exceed $50,000 in direct

costs and is for a period of one year only. The award is not

renewable.

RESEARCH OBJECTIVES

The National Institute on Drug Abuse (NIDA), through the issuance of

this Program Announcement (PA) hopes to facilitate the entry of

beginning investigators into the field of behavioral science

research. It is well-documented that the number of investigators

entering basic behavioral sciences research is declining. This is of

special concern to NIDA because understanding behavioral processes is

fundamental to curbing drug abuse and addiction.

Because of the importance of this public health mission, the pipeline

of behavioral science investigators who will make the next important

discoveries in drug abuse must not run dry. Recently NIDA has pursued

several initiatives to emphasize its interest in the behavioral

sciences. The purpose of this PA is to underscore NIDA's commitment

and interest in expanding the scope of basic behavioral sciences

research in drug abuse. NIDA supports both animal and human basic

research to elucidate underlying behavioral mechanisms, determinants

and correlates of drug abuse (both licit and illicit), and to

characterize the harmful sequelae of drug abuse and addiction.

Animal and human research applications are encouraged in the

following broad areas (specific research examples shown are

illustrative only; research topics will not be restricted to those

listed). While the proposed project is not required to use drugs of

abuse or to study drug abusers in the research protocol, the

application should advance our understanding of and be related to

drug abuse and addiction.

o Behavioral genetic approaches either in animal models (e.g.,

transgenic animals, development of simple high-input behavioral

screens) or human subject studies (e.g., establishment of pedigrees,

twin studies).

o Cognitive effects and causative factors (learning and memory,

information processing, perceptual processes including pain and

analgesia, attention, problem solving, concept formation, spatial

ability, neuropsychology and neurocognition, animal cognition).

o Psychosocial, social and personality factors (psychosocial risk

factors, group and interpersonal processes, risk taking and HIV/AIDS,

social influence, social values, social attitudes and cognition,

persuasion conformity and compliance).

o Motivational bases of behavior (self-control, behavioral

alternatives, craving, appetitive and ingestive behaviors, emotion).

INCLUSION OF WOMEN AND MINORITIES IN RESEARCH INVOLVING HUMAN

SUBJECTS

It is the policy of the NIH that women and members of minority groups

and their subpopulations must be included in all NIH supported

biomedical and behavioral research projects involving human subjects,

unless a clear and compelling rationale and justification is provided

that inclusion is inappropriate with respect to the health of the

subjects or the purpose of the research. This policy results from

the NIH Revitalization Act of 1993 (Section 492B of Public Law

103-43).

All investigators proposing research involving human subjects should

read the "NIH Guidelines For Inclusion of Women and Minorities as

Subjects in Clinical Research," which have been published in the

Federal Register of March 28, 1994 (FR 59 14508-14513) and in the NIH

Guide for Grants and Contracts, Volume 23, Number 11, March 18, 1994.

APPLICATION PROCEDURES

Applications are to be submitted on the grant application form PHS

398 (rev. 5/95). Applications kits are available at most

institutional offices of sponsored research and may be obtained from

the Division of Extramural Outreach and Information Resources,

National Institutes of Health, 6701 Rockledge Drive, MSC 7910,

Bethesda, MD 20892-7910, telephone 301/435-0714, email:

ASKNIH@odrockm1.od.nih.gov.

The title and number of the program announcement must be typed in

Section 2 on the face page of the application. The application

length should not exceed 10 typewritten pages. Additionally, the new

NIH Just-in-Time application procedures apply for B/START-NIDA

submissions such that Other Support and detailed budgetary

information is not required until the application is likely to be

funded. See the NIH Guide for Grants and Contracts, Volume 25, Number

10, March 29, 1996 for further information.

The completed original application and three legible copies must be

sent or delivered to:

DIVISION OF RESEARCH GRANTS

NATIONAL INSTITUTES OF HEALTH

6701 ROCKLEDGE DRIVE, ROOM 1040 - MSC 7710

BETHESDA, MD 20892-7710

BETHESDA, MD 20897 (if using courier/express service)

To permit an expedited review of the application, applicants must

simultaneously send two complete copies to:

Office of Extramural Program Review

National Institute on Drug Abuse

5600 Fishers Lane, Room 10-42

Rockville, MD 20857

In FY 97, the regular receipt date of June 1 for R03 applications

applies. For FY 98 and beyond, there will be two receipt dates per

fiscal year: October 1 and February 1.

REVIEW CONSIDERATIONS

Applications that are complete and responsive to the program

announcement will be evaluated for scientific and technical merit by

appropriate peer reviewers. As part of the merit review, all

applications will receive a written critique.

Scientific reviews will be conducted on receipt of the application.

In about five months, applicants will be notified by NIDA staff

whether or not their application will be funded. No funding will

occur during the months of October and November. Revised B/START-

NIDA applications are not allowed.

Review Criteria

o scientific, technical, or medical significance and originality of

proposed research;

o appropriateness and adequacy of the experimental approach and

methodology proposed to carry out the research;

o availability of the resources necessary to perform the research;

o adequacy of plans to include both genders and minorities as

appropriate for the scientific goals of the research. Plans for the

recruitment and retention of subjects will also be evaluated.

The reviewers will also examine the provisions for the protection of

human and animal subjects, and the safety of the research

environment.

AWARD CRITERIA

It is anticipated that up to $500,000 for FY 1997 will be available

to support projects submitted under this program announcement.

Future years' support will depend upon available appropriations. The

following will be considered in making funding decisions: Quality of

the proposed project as determined by peer review, availability of

funds, and program priority.

INQUIRIES

Inquiries are encouraged. The opportunity to clarify any issues or

questions from potential applicants is welcome.

Direct inquiries regarding programmatic issues to:

Jaylan Turrkan, Ph.D.

Division of Basic Research

National Institute on Drug Abuse

5600 Fishers Lane, Room 10A31

Rockville, MD 20857

Telephone: (301) 443-1263

Email: jaylan@helix.nih.gov

Harold Gordon, Ph.D.

Division of Clinical and Services Research

National Institute on Drug Abuse

5600 Fishers Lane, Room 10A-46

Rockville, MD 20857

Telephone: (301) 443-4877

Email: hg23r@nih.gov

Meyer Glantz, Ph.D.

Division of Epidemiology and Prevention Research

National Institute on Drug Abuse

5600 Fishers Lane, Room 9A-55

Rockville, MD 20857

Telephone: (301) 4432974

Email: mg115g@nih.gov

Direct inquiries regarding fiscal matters to:

Dr. Gary Fleming Grants Management Branch

National Institute on Drug Abuse

5600 Fishers Lane, Room 8A-54

Rockville, MD 20857

Telephone: (301) 443-6710

Email: gf6s@nih.gov

AUTHORITY AND REGULATIONS

This program is described in the Catalog of Federal Domestic

Assistance No. 93.279. Awards are made under authorization of the

Public Health Service Act, Title IV, Part A (Public Law 78-410, as

amended by Public Law 99-158, 42 USC 241 and 285) and administered

under PHS grants policies and Federal Regulations 42 CFR 52 and 45

CFR Part 74. This program is not subject to the intergovernmental

review requirements of Executive Order 12372 or Health Systems Agency

review.

The Public Health Service (PHS) strongly encourages all grant

recipients to provide a smoke-free workplace and promote the non-use

of all tobacco products. In addition, Public Law 103-227, the Pro-

Children Act of 1994, prohibits smoking in certain facilities (or in

some cases, any portion of a facility) in which regular or routine

education, library, day care, health care or early childhood

development services are provided to children. This is consistent

with the PHS mission to protect and advance the physical and mental

health of the American people.

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